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Perth Biotech hopes to help family dogs that treat cancer and has opened up 36 clinical trials of anticancer products. Following ratification by the Animal Care and Ethics Committee of New South Wales, Perth Biotech was approved to implement its PPL-1 product as a last resort for dogs and cancer.
The company hopes that the product can be very early in the human trial phase, has an Adelaide-based patient involved, and will slow growth, leading to retrograde type of advanced tumors. Because dogs cannot be cured with melanoma, double-soft tissue sarcoma, and chemotherapy-resistant lymphoma, they are currently being tested.
Executive chairman Roger Aston said, "Eligible dogs need to fail to take care of all the criteria and try out all human therapeutic methods available. We found this to be a very effective animal model like mice. But when we With a compassionate study, we found that the product actually tastes terrible, even if you mix it with your favorite food.So we changed it to liquid form soft capsules such as fish oil capsules, and the dog is taking very it is good."
He said that the study will be based in Sydney, but if a desperate pet owner wants to move to test, they will not say no. The market for dogs in cancer treatment is estimated to cost about 550 million U.S. dollars in the United States.
Globe valve, also known as cut-off valve, is a mandatory sealing valve, so when the valve is closed, pressure must be applied to the valve disc to force the sealing surface not to leak. When the medium enters the valve from under the valve disc, the resistance that the operating force needs to overcome is the friction force between the valve stem and the packing and the thrust generated by the pressure of the medium. The force to close the valve is greater than the force to open the valve, so the valve stem The diameter of the valve should be large, otherwise the failure of the top of the valve stem will occur. According to the connection method, it is divided into three types: flange connection, thread connection and welding connection. After the appearance of the self-sealing valve, the medium flow direction of the globe valve is changed from the top of the valve disc into the valve cavity. At this time, under the action of the medium pressure, the force to close the valve is small, but the force to open the valve is large, and the diameter of the valve stem can be adjusted accordingly. decrease. At the same time, under the action of the medium, this form of valve is also tighter. my country's valve "Three Chemicals" once stipulated that the flow direction of the globe valve should be from top to bottom. When the globe valve is opened, the opening height of the valve disc is 25% to 30% of the nominal diameter. The flow rate has reached the maximum, indicating that the valve has reached the fully open position. Therefore, the fully open position of the globe valve should be determined by the stroke of the valve disc.
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